How soon after vaccination do dogs show adverse reactions?
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Expert Answer
Within 24 hours of vaccination dogs may show reactions such as lethargy and poor appetite, which is normal and usually disappears in 1 to 2 days. Reactions vary by constitution; some dogs have an allergic reaction with vomiting or breathing difficulty.
That is why vets usually recommend a 30-minute observation after vaccination so help can be given promptly if allergy occurs.