How long do maternal antibodies last in a puppy’s body?

Maternal antibodies in newborn puppies can last up to just over 2 months, but they gradually weaken in the puppy’s body. When maternal antibodies drop below a certain level, they cannot resist some aggressive diseases such as herpesvirus.

Therefore, even if maternal antibodies have not completely disappeared, the puppy may still be infected with infectious diseases. It is generally recommended to vaccinate the puppy 45 days after birth, but if the dog’s constitution is poor, wait until it is healthier before vaccination.