What causes vaccine failure in dogs?

Vaccine failure in dogs can be caused by genetic factors, maternal antibody interference, nutritional factors, and improper vaccination. Some dogs may be born with congenital immune deficiency, leading to vaccine failure. Second, maternal antibody interference is also a common cause.

Newborn puppies all carry some maternal antibodies, so vaccination is generally advised after 45 days of age. In addition, lack of nutrients in the dog’s body can also lead to vaccine failure. Moreover, unqualified vaccine quality or improper vaccination can also cause vaccine failure.